Clinical Outcomes of Diffuse Axonal Injury According to Radiological Grade

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Diffuse Axonal Injury: Pathological and Clinical Aspects

Diffuse traumatic brain injury refers to widespread pattern of injury throughout the brain caused by traumatic disruption of nerve cells, with particular injury to the axons [1]. There are four principal types of traumatic brain injury: diffuse vascular injury, diffuse axonal injury, hypoxic-ischemic encephalopathy and diffuse brain swelling [2]. Clinically, DAI is characterized by generalized ...

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Cognitive sequelae of diffuse axonal injury.

BACKGROUND The results of recent studies on cognitive disability after traumatic brain injury-associated diffuse axonal injury (DAI) are inconsistent. In these studies, the diagnosis of DAI relied on cranial computed tomography. OBJECTIVE To further clarify the extent and severity of a possibly DAI-associated cognitive impairment by the use of magnetic resonance imaging (MRI) and detailed neu...

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Traumatic Brain Injury at Multiple Length Scales: Relating Diffuse Axonal Injury to Discrete Axonal Impairment

The length scales involved in the development of diffuse axonal injury, typically range from the head level (i.e., mechanical loading) to the cellular level, where discrete axonal injuries are located near inclusions. The aim is to investigate the local axonal strains near an inclusion in relation to the tissue level strains of the brain stem during mechanical loading of the head and the result...

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Background: Diffuse axonal injury (DAI) is one of the most common and important pathologic features of traumatic brain injury (TBI). The susceptibility of axons to mechanical injury appears to be due to both their viscoelastic properties and their high organization in white matter tracts. Although axons are supple under normal conditions, they become brittle when exposed to rapid deformations a...

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ژورنال

عنوان ژورنال: Journal of Trauma and Injury

سال: 2018

ISSN: 1738-8767,2287-1683

DOI: 10.20408/jti.2018.31.2.51